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Frequently Asked Questions

Contents

  1. Are probiotics safe?
  2. Can probiotics survive stomach acid?
  3. Can one develop resistance to probiotics?
  4. Can probiotics digest the linings of my intestine?
  5. Do I need a prescription for ZyProbio?
  6. How much ZyProbio should I take daily?
  7. Should the dose be adjusted for body weight?
  8. Can I skip ZyProbio on certain days?
  9. What if I forget to take ZyProbio with my meal? Can I take it after I eat?
  10. Are the capsules easy to swallow?
  11. Should I take the capsules only with water or can it be taken with other beverages?
  12. How should ZyProbio be stored?
  13. Can I take ZyProbio with alcohol?
  14. Is ZyProbio gluten-free? Are there any additives?
  15. Is ZyProbio vegan?
  16. Can I go out in the sun while taking ZyProbio?
  17. Can ZyProbio be given to children?
  18. Can ZyProbio cross-react with other medications or antibiotics?
  19. Can ZyProbio be given to pregnant women or lactating mothers?
  20. How long does it take for probiotics to work?
  21. Should I stop taking my other digestive medications while I am taking ZyProbio?

1. Are Probiotics Safe?

In general, probiotics are safe and have been used for more than 100 years. People who are acutely ill or have a compromised immune system should be concerned about continuing probiotics and should consult their healthcare providers.

2. Can probiotics survive stomach acid?

Most probiotics are resistant to stomach acid and will progress to other parts of the intestines where they are beneficial.

3. Can one develop resistance to probiotics?

Probiotics in the small bowel and colon continue to colonize and metabolize with turnover. One does not develop resistance to probiotics.

4. Can probiotics digest the lining of my intestine?

The linings of the intestine have a protective coating and act as a barrier to resist any damage; probiotics help in building the defense of the intestines.

5. Do I need a prescription for ZyProbio?

You do not need a prescription for ZyProbio. You can purchase it over the counter as a dietary supplement.

6. How much ZyProbio should I take daily?

Take 1 capsule a day before starting your meal.

7. Should the dose be adjusted for body weight?

Based on clinical experience, if your BMI is greater than 30, you should take 2 capsules a day.

8. Can I skip ZyProbio on certain days?

It is recommended to take it daily in order to maintain a high concentration of beneficial bacteria in the gut and to aid in food digestion.

9. What if I forget to take ZyProbio with my meal? Can I take it after I eat?

You can certainly take it after you eat if you forget. Probiotics will continue to function with or without a meal. However, the digestive enzymes work better if taken closer to or with a meal.

10. Are the capsules easy to swallow?

Yes, the capsules are a standard size and are easy to swallow.

11. Should I take the capsules only with water or can it be taken with other beverages?

It is recommended that you should only take ZyProbio with water.

12. How should ZyProbio be stored?

Bottles of ZyProbio should be stored at room temperature. Do not refrigerate.

13. Can I take ZyProbio with alcohol?

Do not take capsules with alcohol, as the enzymes can be denatured.

14. Is ZyProbio gluten-free? Are there any additives?

ZyProbio is free of gluten, soy, chemicals and coloring agents.

15. Is ZyProbio vegan?

Yes, it is 100% vegan. The supplement does not contain any animal or milk sources.

16. Can I go out in the sun while taking ZyProbio?

Yes. There has been no photosensitivity reported with these probiotics.

17. Can ZyProbio be given to children?

There has been no testing done in children. You should consult your doctor or healthcare professional.

18. Can ZyProbio cross-react with other medications or antibiotics?

No testing for this has been done. However, one should avoid taking ZyProbio with other medications simultaneously. You should consult your doctor or healthcare professional with further questions.

19. Can ZyProbio be given to pregnant women or lactating mothers?

You should consult your doctor or healthcare professional before taking it if you are pregnant, trying to get pregnant, or lactating.

20. How long does it take for probiotics to work?

The probiotics do not work instantly. It may take 1-2 weeks before there are changes in the bacterial flora in the gut and the benefits are noticeable. However, the enzymes in ZyProbio should start functioning immediately to digest food and may provide relief in very short period of time.

21. Should I stop taking my other digestive medications while I am taking ZyProbio?

You should not alter your medications without checking with your health care professional.

References

  1. Biesiekierski JR, Newnham ED, Irving PM, et al. Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double-blind randomized placebo-controlled trial. Am J Gastroenterol. 2011;106(3):508-515. doi:10.1038/ajg.2010.487
  2. Brenner DM, Moeller MJ, Chey WD, Schoenfeld PS. The utility of probiotics in the treatment of irritable bowel syndrome: a systematic review. Am J Gastroenterol. 2009;104(4):1033-1050. doi:10.1038/ajg.2009.25
  3. Chadwick VS, Chen W, Shu D, et al. Activation of the mucosal immune system in irritable bowel syndrome. Gastroenterology. 2002;122(7):1778-1783. doi:10.1053/gast.2002.33579
  4. Cuomo R, Andreozzi P, Zito FP, Passananti V, De Carlo G, Sarnelli G. Irritable bowel syndrome and food interaction. World J Gastroenterol. 2014 Jul 21;20(27):8837-45. doi: 10.3748/wjg.v20.i27.8837.
  5. Gibson PR, Shepherd SJ. Evidence-based dietary management of functional gastrointestinal symptoms: the FODMAP approach. J Gastroenterol Hepatol. 2010;25:252–258.
  6. Hungin AP, Chang L, Locke GR, Dennis EH, Barghout V. Irritable bowel syndrome in the United States: prevalence, symptom patterns, and impact. Aliment Pharmacol Ther. 2005;21:1365–1375.
  7. Kajander K, Hatakka K, Poussa T, Färkkilä M, Korpela R. A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6-month intervention. Aliment Pharmacol Ther. 2005;22(5):387-394. doi:10.1111/j.1365-2036.2005.02579.x
  8. Lee NK, Kim WS, Paik HD. Bacillusstrains as human probiotics: characterization, safety, microbiome, and probiotic carrier. Food Sci Biotechnol. 2019 Oct 8;28(5):1297-1305. doi: 10.1007/s10068-019-00691-9. eCollection 2019 Oct.
  9. Lin HC. Small intestinal bacterial overgrowth: a framework for understanding irritable bowel syndrome. JAMA. 2004;292:852–858.
  10. Money ME, Walkowiak J, Virgilio C, Talley NJ. Pilot study: a randomised, double blind, placebo controlled trial of pancrealipase for the treatment of postprandial irritable bowel syndrome-diarrhoea. Frontline Gastroenterol. 2011;2(1):48-56. doi:10.1136/fg.2010.002253
  11. Narula A, Amey M, Kramer J, Marconis S. (Zygluten) Digestive Enzyme Supplement Therapy for Diabetic Gastroparesis with Gastric Bezoar. American Journal of Gastroenterology. October 2018, 113: S697-S698.
  12. Narula AP. Evaluation of Safety and Efficacy of Dietary Supplement ZyGluten In Patients with Gluten Sensitivity. Journal of Gluten Sensitivity. 2015 Jan; 14(1):17-21. https://www.celiac.com/articles.html/evaluation-of-safety-and-efficacy-of-dietary-supplement-zygluten-in-patients-with-gluten-sensitivity-r3749/
  13. Nithya V., Halami P. Evaluation of the probiotic characteristics of Bacillusspecies isolated from different food sources. Ann. Microbiol. 2013;63:129–137. doi: 10.1007/s13213-012-0453-4.
  14. Niv E, Naftali T, Hallak R, Vaisman N. The efficacy of Lactobacillus reuteri ATCC 55730 in the treatment of patients with irritable bowel syndrome–a double blind, placebo-controlled, randomized study. Clin Nutr. 2005;24(6):925-931. doi:10.1016/j.clnu.2005.06.001
  15. O’Mahony L, McCarthy J, Kelly P, et al. Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology. 2005;128(3):541-551. doi:10.1053/j.gastro.2004.11.050
  16. Ong DK, Mitchell SB, Barrett JS, et al. Manipulation of dietary short-chain carbohydrates alters the pattern of gas production and genesis of symptoms in irritable bowel syndrome. J Gastroenterol Hepatol. 2010;25:1366–1373.
  17. Probiotics: What You Need To Know. (2019, August). Retrieved November 30, 2020, from https://www.nccih.nih.gov/health/probiotics-what-you-need-to-know
  18. Tompkins T.A., Xu X., Ahmarani J. A comprehensive review of post-market clinical studies performed in adults with an Asian probiotic formulation. Benef. Microbes. 2010;1:93–106. doi: 10.3920/BM2008.1005.
  19. Tuck CJ, Taylor KM, Gibson PR, Barrett JB, Muir JG. (2017, August). Increasing Symptoms in Irritable Bowel Symptoms With Ingestion of Galacto-Oligosaccharides Are Mitigated by [alpha]-Galactosidase Treatment, Am J Gastroenterol, 113:124–134.
  20. Urdaci M.C., Bressollier P., Pinchuk I. Bacillus clausiiprobiotic strains: Antimicrobial and immunomodulatory activities. J. Clin. Gastroenterol. 2004;38:86–90. doi: 10.1097/01.mcg.0000128925.06662.69.